Description

Thesinine CAS NO 488-02-8 is a pyrrolizidine alkaloid of significant interest in pharmaceutical and biochemical research. This compound serves as a crucial reference standard and intermediate for the development of analytical methods and pharmacological studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and manufacturers of high-purity fine chemicals.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, purity assessment, and quantification of pyrrolizidine alkaloids in drug substances and herbal products.
• Biochemical Research: Serves as a key intermediate or substrate in metabolic pathway studies and for investigating the biological activity of natural products.
• Analytical Chemistry: Employed in method development and validation for techniques like HPLC, LC-MS, and GC-MS to detect and quantify related alkaloids.
• Toxicology Studies: Used as a model compound in research focused on the hepatotoxicity and genotoxicity associated with pyrrolizidine alkaloids.
• Natural Product Isolation & Synthesis: Acts as a marker compound for the quality control of plant extracts and as a starting material or target in synthetic chemistry.

Basic Information

Product Name	Thesinine
CAS No.	488-02-8
Molecular Formula	C16H25NO5
Molecular Weight	311.37 g/mol
Synonyms	1,2-Didehydro-7-hydroxy-8-(hydroxymethyl)-6,7-seco-8-angeloyloxyretronecine; 7-Hydroxy-8-(hydroxymethyl)-6,7-seco-8-angeloyloxy-1,2-didehydroretronecine; Thesinin; (-)-Thesinine; Thesinine alkaloid
EINECS	Contact for details

Quality Control

Our Thesinine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.