Description

(+)-α-Isolupanine CAS NO 486-87-3 is a specific stereoisomer of the quinolizidine alkaloid isolupanine, characterized by its defined chiral center. This compound is of significant interest in advanced chemical research and development, particularly for its role as a key chiral building block and reference standard. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require high-purity, structurally defined alkaloids for synthesis, analytical method development, and biological activity studies.

Application

• Pharmaceutical Intermediate: Serves as a chiral precursor or scaffold in the synthesis of novel drug candidates, particularly those targeting neurological or biological pathways.
• Analytical Reference Standard: Used as a high-purity standard in chromatographic (HPLC, GC) and spectroscopic methods for the identification and quantification of alkaloids in complex matrices.
• Biochemical Research: Employed in pharmacological and toxicological studies to investigate the biological activity and mechanism of action of quinolizidine alkaloids.
• Fine Chemical Synthesis: Acts as a specialized building block for the preparation of more complex, value-added chemical entities in asymmetric synthesis.
• Agrochemical Development: Investigated for potential use in the development of new plant-derived bioactive agents or natural product-inspired crop protection solutions.

Basic Information

Product Name	(+)-α-Isolupanine
CAS No.	486-87-3
Molecular Formula	C15H24N2O
Molecular Weight	248.37 g/mol
Synonyms	(+)-α-Isolupanine; (7R,9S)-7,15-Didehydro-10-oxosparteine; (+)-Isolupanine; α-Isolupanine; (+)-10-Oxosparteine; Lupan-10-one, 7,15-didehydro-, (7R,9S)-; Spartein-10-one
EINECS	207-646-5

Quality Control

Our (+)-α-Isolupanine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by chromatographic techniques (HPLC). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.