Description

Harmane is a naturally occurring β-carboline alkaloid with significant biological and chemical research interest. This compound serves as a crucial reference standard and building block in the development of novel pharmaceutical agents and biochemical tools. It is primarily utilized by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers engaged in neuroscience, medicinal chemistry, and analytical method development.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and study of bioactive molecules targeting neurological pathways.
• Biochemical Research: Employed as a tool compound in studies of enzyme inhibition, receptor binding, and cellular signaling mechanisms.
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for method validation, calibration, and quality control in HPLC, LC-MS, and GC-MS analyses.
• Medicinal Chemistry: Acts as a core scaffold for the design and synthesis of new chemical entities with potential therapeutic applications.
• Neuroscience Studies: Investigated for its interactions with various neurotransmitter systems and its role as a potential endogenous modulator.

Basic Information

Product Name	Harmane
CAS No.	486-84-0
Molecular Formula	C₁₃H₁₀N₂
Molecular Weight	194.24 g/mol
Synonyms	1-Methyl-9H-pyrido[3,4-b]indole; Aribine; 4,9-Dihydro-1-methyl-3H-pyrido[3,4-b]indole; 1-Methylnorharman; Passiflorin; Loturine; Telepathine; Banisterine; Yageine; Leucoharmane
EINECS	207-645-7

Quality Control

Our Harmane is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support research and industrial applications requiring material traceability and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.