Description

(-)-Lupinine CAS NO 486-70-4 is a naturally occurring quinolizidine alkaloid, serving as a key chiral building block and reference standard in advanced chemical synthesis. Its defined stereochemistry and rigid bicyclic structure make it a valuable intermediate for pharmaceutical research and the development of bioactive compounds. This high-purity material is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients or analytical methods.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly those targeting neurological and anti-inflammatory pathways.
• Reference Standard: Used for the qualitative and quantitative analysis of lupinine and related alkaloids in research, quality control, and regulatory testing.
• Agrochemical Research: Serves as a lead compound or synthetic intermediate in the development of new plant protection agents with potential insecticidal or fungicidal activity.
• Natural Product Chemistry: Employed in the study, isolation, and structural elucidation of complex plant alkaloids and their derivatives.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or template in stereoselective reactions to construct complex molecular architectures.
• Biochemical Research: Investigated for its biological activity and potential interactions with enzymes and receptors in pharmacological studies.

Basic Information

Product Name	(-)-Lupinine
CAS No.	486-70-4
Molecular Formula	C10H19NO
Molecular Weight	169.26 g/mol
Synonyms	(-)-Lupinan-3-ol; (1R,9aR)-Octahydro-2H-quinolizine-1-methanol; L-Lupinine; (1R,9aR)-1-Hydroxymethylquinolizidine; Lupinine; (1R,9aR)-1-(Hydroxymethyl)quinolizidine
EINECS	207-637-7

Quality Control

Our (-)-Lupinine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to meeting the stringent requirements of research and development, with quality systems designed to support cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-19° to -23° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.