Description

Vasicinone CAS NO 486-64-6 is a naturally occurring quinazoline alkaloid of significant interest in pharmaceutical research and development. This compound serves as a key intermediate and a privileged scaffold for synthesizing novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery, particularly for respiratory and neurological applications. Its unique structure makes it a valuable building block for medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of vasicine, peganine, and other related alkaloids with therapeutic potential.
• Respiratory Research: Investigated for its bronchodilatory and anti-asthmatic properties, forming the basis for developing new respiratory treatments.
• Neurological Agent Development: Studied for potential acetylcholinesterase inhibitory activity, relevant to cognitive disorder and Alzheimer's disease research.
• Medicinal Chemistry Scaffold: Used as a core structure for designing and synthesizing novel quinazoline-based drug candidates.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for the identification and quantification of related alkaloids in plant extracts or finished products.
• Biochemical Research: Utilized in pharmacological studies to understand mechanism of action and structure-activity relationships (SAR) of quinazoline alkaloids.

Basic Information

Item	Detail
Product Name	Vasicinone
CAS No.	486-64-6
Molecular Formula	C₁₁H₁₀N₂O₂
Molecular Weight	202.21 g/mol
Synonyms	Vasicinone; 7-Hydroxy-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-9-one; Peganone; 1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazolin-9-one, 7-hydroxy-; (-)-Vasicinone; Vasakin; (3S)-3-Hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9(4H)-one
EINECS	207-642-5

Quality Control

Our Vasicinone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and specifications can be tailored to meet specific project requirements, including those for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.