Description

Coclaurine CAS NO 486-39-5 is a naturally occurring isoquinoline alkaloid, recognized for its role as a key biosynthetic precursor to a wide range of benzylisoquinoline alkaloids. This compound is of significant interest in pharmaceutical research and development due to its structural importance. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in alkaloid synthesis, neuroscience research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the semi-synthesis of complex medicinal alkaloids, such as certain muscle relaxants and potential neuroactive compounds.
• Biochemical Research: Used as a reference standard and precursor in studies of alkaloid biosynthesis pathways within plants.
• Neuroscience Studies: Investigated for its interactions with neurotransmitter systems, serving as a tool compound in pharmacological research.
• Fine Chemical Synthesis: Employed in organic synthesis to construct more complex isoquinoline-based molecular architectures for various applications.
• Natural Product Isolation & Analysis: Serves as a benchmark for the identification and quantification of related alkaloids in plant extracts and natural products.

Basic Information

Product Name	Coclaurine
CAS No.	486-39-5
Molecular Formula	C17H19NO3
Molecular Weight	285.34 g/mol
Synonyms	Coclaurin; (1R)-1-[(4-Hydroxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-isoquinolinediol; Norcoclaurine; Higenamine 4'-O-methyl ether; 1-[(4-Hydroxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
EINECS	207-632-7

Quality Control

Our Coclaurine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.