Description

(3β,20α)-11-Methoxyyohimban-17-One CAS NO 486-07-7 is a specialized indole alkaloid derivative, structurally related to yohimbine, known for its significance as a key intermediate and reference standard in pharmaceutical research and development. Its precise stereochemistry makes it a valuable building block for synthesizing novel compounds targeting neurological and cardiovascular pathways. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, well-characterized materials for drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex alkaloids and potential therapeutic agents.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.
• Biochemical Research: Employed in studies investigating adrenergic receptor activity and other neurological mechanisms.
• Fine Chemical Synthesis: A valuable starting material for organic chemists creating novel molecular libraries for screening.
• Academic Research: Utilized in universities and research institutes for studying natural product chemistry and alkaloid biosynthesis.

Basic Information

Product Name	(3β,20α)-11-Methoxyyohimban-17-One
CAS No.	486-07-7
Molecular Formula	C₂₁H₂₆N₂O₃
Molecular Weight	354.44 g/mol
Synonyms	11-Methoxyyohimban-17-one; 11-Methoxy-yohimban-17-one; 17-Oxo-11-methoxy-yohimban; 11-Methoxy-17-oxoyohimban; 3β,20α-11-Methoxyyohimban-17-one; Yohimban-17-one, 11-methoxy-; 11-Methoxyyohimbinone; (3beta,20alpha)-11-Methoxyyohimban-17-One
EINECS	207-632-3

Quality Control

Our (3β,20α)-11-Methoxyyohimban-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.