Description

6-Amino-9-[3,4-Dihydroxy-5-[(Hydroxy-Sulfooxy-Phosphoryl)Oxymethyl]Oxolan-2-Yl]-Purine is a high-purity nucleotide derivative, also known as Adenosine 5'-Monophosphosulfate (APS). This compound serves as a critical biochemical intermediate and cofactor in numerous enzymatic sulfotransferase reactions. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors, particularly for studies involving sulfation pathways, drug metabolism, and enzyme kinetics.

Application

• Biochemical Research: Essential cofactor for in vitro studies of sulfotransferase enzymes (SULTs) involved in phase II drug metabolism and hormone regulation.
• Pharmaceutical Development: Used in the synthesis and metabolic profiling of sulfated drug candidates and prodrugs.
• Diagnostic Reagent Manufacturing: A key component in enzymatic assay kits designed to measure sulfotransferase activity for clinical and research diagnostics.
• Enzymology Studies: Serves as the sulfate donor substrate for investigating the kinetics and mechanisms of sulfation reactions.
• Glycobiology & Proteomics Research: Utilized in the study of sulfated glycans, proteoglycans, and post-translational modifications.
• Reference Standard: High-purity grade suitable for use as an analytical reference standard in HPLC, LC-MS, and other chromatographic methods.

Basic Information

Product Name	6-Amino-9-[3,4-Dihydroxy-5-[(Hydroxy-Sulfooxy-Phosphoryl)Oxymethyl]Oxolan-2-Yl]-Purine
CAS No.	485-84-7
Molecular Formula	C10H15N5O10P2S
Molecular Weight	483.26 g/mol
Synonyms	Adenosine 5'-Monophosphosulfate; Adenosine 5'-Phosphosulfate; APS; 5'-Adenylyl sulfate; Adenosine 5'-phosphosulfuric acid; Adenosine phosphosulfate; Sulfoadenosine phosphate; Adenosine 5'-(dihydrogen phosphosulfate)
EINECS	207-622-5

Quality Control

Our 6-Amino-9-[3,4-Dihydroxy-5-[(Hydroxy-Sulfooxy-Phosphoryl)Oxymethyl]Oxolan-2-Yl]-Purine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, desiccate and keep frozen. Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	2.0 - 4.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.