Description

Cinchonidine is a naturally occurring alkaloid of the cinchona tree, recognized for its distinct stereochemistry and role as a chiral auxiliary. This compound is a critical building block and resolving agent in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries where precise chirality control is paramount.

Application

• As a chiral ligand or catalyst in asymmetric synthesis and hydrogenation reactions.
• As a resolving agent for the separation of racemic mixtures of carboxylic acids and other chiral compounds.
• In pharmaceutical research for the development of enantiomerically pure active pharmaceutical ingredients (APIs).
• As a reference standard in analytical chemistry for method development and quality control.
• In academic and industrial research exploring novel catalytic systems and organic transformations.
• As a precursor or intermediate in the synthesis of more complex alkaloids and specialty chemicals.

Basic Information

Product Name	Cinchonidine
CAS No.	485-71-2
Molecular Formula	C19H22N2O
Molecular Weight	294.39 g/mol
Synonyms	(8S,9R)-Cinchonidine; (8α,9R)-Cinchonan-9-ol; α-(5-Vinyl-2-quinuclidinyl)-4-quinolinemethanol; Cinchonan-9-ol, (8α,9R)-; Cinchovatine; Dihydrocinchonine; Cupreine, dihydro-
EINECS	207-614-1

Quality Control

Our Cinchonidine is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure it meets high-purity standards suitable for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	205°C - 210°C
Specific Rotation	-109° to -112° (c=1 in ethanol)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.