Description

9-Epi-Cinchonine is a stereoisomer of the natural alkaloid cinchonine, a key member of the cinchona alkaloid family. This compound serves as a valuable chiral building block and reference standard in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and chemical manufacturers specializing in asymmetric catalysis, medicinal chemistry, and the development of active pharmaceutical ingredients (APIs).

Application

• Asymmetric Synthesis Catalyst: Employed as a chiral ligand or organocatalyst in stereoselective chemical reactions.
• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of novel therapeutic agents.
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC and LC-MS analysis within pharmaceutical and academic labs.
• Medicinal Chemistry Research: Acts as a core scaffold for structure-activity relationship (SAR) studies and biological screening.
• Chemical Biology Studies: Utilized as a probe to study biological pathways and enzyme interactions due to its specific stereochemistry.

Basic Information

Product Name	9-Epi-Cinchonine
CAS No.	485-70-1
Molecular Formula	C19H22N2O
Molecular Weight	294.39 g/mol
Synonyms	(9R)-Cinchonan-9-ol; (8α,9R)-Cinchonan-9-ol; 9-epi-Cinchonine; Cinchonan-9-ol, (8α,9R)-; 9-Epicinchonine; Cinchonine, 9-epi-; (R)-9-Hydroxycinchonane
EINECS	207-621-8

Quality Control

Our 9-Epi-Cinchonine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.