Description

Kokusaginine CAS NO 484-08-2 is a naturally occurring furoquinoline alkaloid, a class of compounds known for their diverse biological activities. This high-purity reference standard is essential for research and development in life sciences, providing a critical tool for pharmacological studies and analytical method development. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and academic institutions focused on natural product chemistry and drug discovery.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the identification, purity assessment, and quantification of kokusaginine in raw materials and finished products.
• Biochemical Research: Used as a key intermediate or active investigational compound in studies exploring its pharmacological properties, such as anti-inflammatory, antimicrobial, or cytotoxic activities.
• Analytical Method Development: Employed as a primary standard to develop and validate analytical methods, including High-Performance Liquid Chromatography (HPLC), Liquid Chromatography-Mass Spectrometry (LC-MS), and Thin-Layer Chromatography (TLC).
• Natural Product Isolation & Synthesis: Acts as a benchmark for the isolation of similar alkaloids from plant sources and as a target molecule in synthetic organic chemistry research.
• Quality Control (QC) & Quality Assurance (QA): Integral for in-house QC/QA protocols in nutraceutical and phytopharmaceutical companies to ensure product consistency and authenticity.

Basic Information

Product Name	Kokusaginine
CAS No.	484-08-2
Molecular Formula	C₁₄H₁₃NO₄
Molecular Weight	259.26 g/mol
Synonyms	4,7-Dimethoxyfuro[2,3-b]quinoline; 7,8-Dimethoxy-2H-furo[2,3-h]quinolin-2-one; Kokusaginin; Maculosidine (Note: Maculosidine is a very close structural analog, often used interchangeably in literature); NSC 51046; Furoquinoline alkaloid
EINECS	207-603-4

Quality Control

Our Kokusaginine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We support compliance with cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.