Description

[13As,(-)]-5,8,13,13A-Tetrahydro-3,10-Dimethoxy-6H-Dibenzo[A,G]Quinolizine-2,11-Diol is a high-purity alkaloid compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate and reference standard for the synthesis and analysis of complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of neurological and cardiovascular therapeutics, as well as by analytical laboratories requiring certified reference materials for quality control.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel alkaloid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference compound in studies investigating receptor binding, enzyme inhibition, and other pharmacological mechanisms.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for HPLC, LC-MS, and NMR analysis in quality control laboratories.
• Academic Research: Employed in university and institutional labs for synthetic chemistry projects and the study of isoquinoline alkaloid derivatives.
• Preclinical Development: Utilized in the early-stage development of potential drug candidates targeting the central nervous system.

Basic Information

Product Name	[13As,(-)]-5,8,13,13A-Tetrahydro-3,10-Dimethoxy-6H-Dibenzo[A,G]Quinolizine-2,11-Diol
CAS No.	483-45-4
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	(-)-Corytuberine; (S)-Corytuberine; L-Corytuberine; 2,11-Dihydroxy-3,10-dimethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine; NSC 169865; Corytuberine
EINECS	207-598-9

Quality Control

Our production of [13As,(-)]-5,8,13,13A-Tetrahydro-3,10-Dimethoxy-6H-Dibenzo[A,G]Quinolizine-2,11-Diol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to prevent oxidation and absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.