Description

(S)-Isocorypalmine CAS NO 483-34-1 is a high-purity, optically active tetrahydroprotoberberine alkaloid of significant interest in advanced research and development. This compound serves as a critical chiral building block and reference standard for investigating neurological pathways and receptor interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of high-value fine chemicals focused on neuroscience and medicinal chemistry.

Application

• Pharmaceutical Research & Development: Acts as a key intermediate and reference standard in the synthesis and study of novel central nervous system (CNS) active compounds.
• Neuroscience Studies: Used as a pharmacological tool to investigate dopaminergic and other neurotransmitter systems, aiding in the understanding of neurological mechanisms.
• Analytical Reference Standard: Serves as a high-purity certified standard for qualitative and quantitative analysis (HPLC, LC-MS) in quality control and method development laboratories.
• Medicinal Chemistry: Employed as a chiral scaffold for structure-activity relationship (SAR) studies aimed at developing new therapeutic agents.
• Biochemical Assays: Utilized in in vitro assays to study enzyme inhibition and receptor binding affinity.
• Fine Chemical Synthesis: Functions as a specialized intermediate for the custom synthesis of complex, biologically active molecules.

Basic Information

Product Name	(S)-Isocorypalmine
CAS No.	483-34-1
Molecular Formula	C₂₀H₂₃NO₄
Molecular Weight	341.40 g/mol
Synonyms	(S)-Isocorypalmine; (-)-Isocorypalmine; (13aS)-2,3,9,10-Tetramethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-isoquinolino[2,1-b]isoquinoline; NSC 158563; Isocorypalmine; (S)-Form of Isocorypalmine
EINECS	Contact for details

Quality Control

Our (S)-Isocorypalmine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the stringent requirements for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider sealing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.