Description

Cephaeline CAS NO 483-17-0 is a naturally occurring alkaloid, structurally related to emetine, primarily extracted from the roots of plants like *Cephaelis ipecacuanha*. This compound serves as a critical pharmacological reference standard and a key intermediate in the synthesis of more complex therapeutic agents. It is essential for research and development in the pharmaceutical and life sciences sectors, particularly for studies involving emetic activity, antiprotozoal effects, and chemical synthesis. Industries requiring high-purity biochemicals for analytical testing, method development, or advanced organic synthesis will find this product indispensable.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity testing, and assay calibration of related pharmaceutical products in QC/QA laboratories.
• Biochemical Research: Serves as a key reagent in pharmacological studies investigating its emetic, expectorant, and potential antiprotozoal properties.
• Organic Synthesis Intermediate: Acts as a sophisticated starting material or precursor for the synthesis of derivatives and more complex alkaloid-based compounds.
• Analytical Chemistry: Employed as a high-purity standard in chromatographic methods (HPLC, TLC) for method development and validation.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in natural product chemistry, pharmacology, and toxicology.

Basic Information

Product Name	Cephaeline
CAS No.	483-17-0
Molecular Formula	C₂₈H₃₈N₂O₄
Molecular Weight	466.62 g/mol
Synonyms	Cephaeline; (+)-Cephaeline; Cephaelin; 1,2,3,4,6,7,12,12b-Octahydro-2-[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolyl]methyl]-9,10-dimethoxyindolo[2,3-a]quinolizine; NSC 32946; Psychotrine methyl ether (demethylated form)
EINECS	207-598-7

Quality Control

Our Cephaeline is produced and handled under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by spectroscopic methods (IR, NMR), and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) documenting all specifications and test results is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.