Description

Rotundine is a naturally occurring isoquinoline alkaloid, recognized for its significant pharmacological properties. This high-purity compound is essential for research and development in the pharmaceutical and nutraceutical sectors, where consistent quality and reliable supply are paramount. It is primarily utilized by manufacturers and research institutions focused on developing therapeutic agents and standardized botanical extracts.

Application

• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of advanced pharmaceutical compounds targeting the central nervous system.
• Reference Standards & Analytical Testing: Used as a certified reference material (CRM) for quality control, method development, and validation in analytical laboratories.
• Biochemical & Pharmacological Research: Employed in preclinical studies to investigate its sedative, analgesic, and potential neuroprotective mechanisms of action.
• Nutraceutical & Dietary Supplement Formulation: Incorporated into formulations aimed at promoting relaxation and supporting natural sleep cycles, following appropriate regulatory compliance.
• Academic Research: Utilized in university and institutional labs for chemical, biological, and pharmacological research projects.

Basic Information

Product Name	Rotundine
CAS No.	483-14-7
Molecular Formula	C21H25NO4
Molecular Weight	355.43 g/mol
Synonyms	L-Tetrahydropalmatine; Gindarine; NSC-169015; (S)-Corydalis B; 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine; Rotundin; L-THP
EINECS	207-598-7

Quality Control

Our Rotundine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP guidelines and relevant pharmacopeial standards for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; appropriate handling procedures should be followed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.