Description

(3β,20α)-17α-Hydroxyyohimban-16β-Carboxylic Acid Methyl Ester is a key indole alkaloid derivative and a significant intermediate in the synthesis of complex pharmaceutical compounds. This high-purity intermediate is critical for ensuring the quality and consistency of downstream active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex indole alkaloid-based APIs.
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new drug candidates targeting neurological and cardiovascular systems.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating alkaloid biosynthesis pathways and their biological activities.

Basic Information

Product Name	(3β,20α)-17α-Hydroxyyohimban-16β-Carboxylic Acid Methyl Ester
CAS No.	483-09-0
Molecular Formula	C₂₁H₂₆N₂O₃
Molecular Weight	354.45 g/mol
Synonyms	Methyl (3β,20α)-17α-hydroxyyohimban-16β-carboxylate; Methyl 17α-hydroxyyohimban-16β-carboxylate; 16β-Carbomethoxy-17α-hydroxyyohimban; Ajmalicine intermediate; Raubasine precursor; Tetrahydroalstonine related compound; Yohimban-16β-carboxylic acid, 17α-hydroxy-, methyl ester, (3β,20α)-
EINECS	207-598-5

Quality Control

Our (3β,20α)-17α-Hydroxyyohimban-16β-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.