Description

(3β,20α)-11,17α-Dimethoxyyohimban-16β-Methanol CAS NO 483-00-1 is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for the development of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules. The compound's defined stereochemistry and functional groups make it a valuable building block for medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential central nervous system (CNS) active drugs and other specialized alkaloid-based pharmaceuticals.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and compound identification.
• Medicinal Chemistry Research: Employed as a scaffold or building block for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Biochemical Research: Utilized in studies investigating alkaloid biosynthesis pathways, receptor binding assays, and other pharmacological research applications.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of complex, high-value organic molecules for various industrial and academic purposes.

Basic Information

Product Name	(3β,20α)-11,17α-Dimethoxyyohimban-16β-Methanol
CAS No.	483-00-1
Molecular Formula	C22H28N2O3
Molecular Weight	368.47 g/mol
Synonyms	11,17α-Dimethoxy-18β-hydroxyyohimban-16β-carboxaldehyde; 16β-Carboxy-11,17α-dimethoxyyohimban; 3β,20α-11,17α-Dimethoxyyohimban-16β-methanol; Yohimbine derivative; 11,17-Dimethoxyyohimban-16-methanol; (3beta,20alpha)-11,17alpha-Dimethoxyyohimban-16beta-methanol; 16beta-Hydroxymethyl-11,17alpha-dimethoxyyohimban
EINECS	Contact for details

Quality Control

Our (3β,20α)-11,17α-Dimethoxyyohimban-16β-Methanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.