Description

(3β,20α)-16,17-Didehydro-11-Methoxy-19α-Methyl-18-Oxayohimban-16-Carboxylic Acid Methyl Ester CAS NO 482-95-1 is a complex indole alkaloid derivative, recognized for its significance as a key synthetic intermediate and a structural analog of bioactive natural products. This compound is valued in advanced pharmaceutical research for its potential role in developing novel therapeutic agents targeting the central nervous system. It is primarily sought by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of specialized alkaloids and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex alkaloid-based drug candidates and reference standards.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies aimed at discovering new neuroactive or cardiovascular agents.
• Biochemical Tool Compound: Employed in pharmacological research to study receptor interactions and enzyme inhibition mechanisms related to indole alkaloid pathways.
• Reference Standard: Provides a high-purity material for analytical method development, validation, and quality control in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional laboratories for synthetic organic chemistry projects and the study of yohimbane-related alkaloids.
• Fine Chemical Synthesis: Acts as a specialized precursor for the custom synthesis of more complex, tailored molecules for client-specific R&D projects.

Basic Information

Item	Detail
Product Name	(3β,20α)-16,17-Didehydro-11-Methoxy-19α-Methyl-18-Oxayohimban-16-Carboxylic Acid Methyl Ester
CAS No.	482-95-1
Molecular Formula	C22H26N2O4
Molecular Weight	382.46 g/mol
Synonyms	Methyl (3β,20α)-16,17-didehydro-11-methoxy-19α-methyl-18-oxayohimban-16-carboxylate; 11-Methoxy-19α-methyl-18-oxayohimban-16-carboxylic acid methyl ester; Alstoniline; Alstoniline methyl ester; 18-Oxaalstoniline; Akuammiline analog; Yohimbane derivative; Oxayohimban ester
EINECS	Contact for details

Quality Control

Our production of (3β,20α)-16,17-Didehydro-11-Methoxy-19α-Methyl-18-Oxayohimban-16-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all specified parameters to ensure the material meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.