Description

Sarpagine is a naturally occurring indole alkaloid isolated from various plant species, including those from the *Rauwolfia* genus. This compound serves as a crucial intermediate and reference standard in pharmaceutical research and development, particularly for its structural and potential biological significance. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on alkaloid chemistry, neuroscience, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical testing, method development, and quality control in drug discovery and natural product research.
• Biochemical Research: Employed in studies investigating the biological activity, structure-activity relationships (SAR), and metabolic pathways of indole alkaloids.
• Organic Synthesis Intermediate: Serves as a key chiral building block or precursor for the semi-synthesis of more complex alkaloids and novel chemical entities.
• Neuroscience Research: Utilized in *in vitro* studies to explore potential interactions with neurological targets, given its structural relation to other bioactive alkaloids.
• Natural Product Isolation & Analysis: Acts as a benchmark compound for the identification and quantification of sarpagine and related alkaloids in plant extracts and herbal preparations.

Basic Information

Product Name	Sarpagine
CAS No.	482-68-8
Molecular Formula	C19H22N2O2
Molecular Weight	310.39 g/mol
Synonyms	16-Episarpagine; (16R)-19,20-Didehydro-17,18-didehydroxysarpagan-16-methanol; Sarpagan-17,18-diol, 19,20-didehydro-16-epi-; Alkaloid Sarpagine; NSC 146051; 10,11-Dimethoxy-17-methyl-17-azapentacyclo[12.3.1.0²,¹⁰.0⁴,⁹.0¹³,¹⁸]octadeca-2,4(9),5,7,13,15-hexaen-17-ol
EINECS	Contact for details

Quality Control

Our Sarpagine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.