Description

Aporphine is a naturally occurring alkaloid and a key structural scaffold in medicinal chemistry, derived from the isoquinoline family. Its unique tetracyclic framework makes it a privileged structure for developing novel bioactive compounds, offering significant value in pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors focused on neuroscience, oncology, and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Neuroscience Research: Used as a reference standard and pharmacological tool in studies investigating dopamine receptor interactions and neurodegenerative disease models.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to develop new analogs with optimized potency and selectivity.
• Natural Product Synthesis: Employed in the total or semi-synthesis of complex natural products containing the aporphine skeleton.
• Biochemical Assays: Utilized as a ligand in receptor binding assays and enzymatic studies to evaluate biological activity.
• Academic & Contract Research: Fundamental for university laboratories and CROs (Contract Research Organizations) conducting basic research in alkaloid chemistry and pharmacology.

Basic Information

Product Name	Aporphine
CAS No.	478-57-9
Molecular Formula	C17H17N
Molecular Weight	235.33 g/mol
Synonyms	4H-Dibenzo[de,g]quinoline, 5,6,6a,7-Tetrahydro-; NSC 56310; 6aβ-Aporphine; 1,2,9,10-Tetramethoxyaporphine (referring to specific derivatives); Aporphine alkaloid core
EINECS	207-531-3

Quality Control

Our Aporphine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data including HPLC purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is supplied with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.