Description

Isotetrandrine is a bisbenzylisoquinoline alkaloid derived from natural sources, recognized for its distinct pharmacological profile. This compound is valued in research and development for its potential as a lead structure in drug discovery and as a reference standard. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors. Our supply ensures high purity and batch-to-batch consistency to meet the stringent demands of these applications.

Application

• Pharmaceutical Research: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of new therapeutic agents.
• Biochemical Studies: Used as a selective tool compound in pharmacological research to study calcium channel modulation and other cellular mechanisms.
• Natural Product Chemistry: Employed as a purified standard for the analysis and quality control of plant extracts and herbal formulations.
• Academic & Institutional Research: Provides a high-purity compound for fundamental studies in medicinal chemistry and pharmacology.
• Preclinical Development: Utilized in in-vitro and in-vivo studies to investigate efficacy, pharmacokinetics, and safety profiles.

Basic Information

Product Name	Isotetrandrine
CAS No.	477-57-6
Molecular Formula	C38H42N2O6
Molecular Weight	622.75 g/mol
Synonyms	Isotetrandrine; (+)-Isotetrandrine; NSC 336579; (1S)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman; Fanchinin; Hanfangchin A; Isotetrandrin; Isotetrandrine (alkaloid)
EINECS	207-516-5

Quality Control

Our Isotetrandrine is produced and tested under a strict quality management system. Each batch is analyzed to confirm identity, purity, and impurity profiles using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all test results against established specifications. We support compliance with cGMP and research-grade standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.