Description

Colchicoside is a naturally occurring tropolone alkaloid glycoside derived from plants of the genus *Colchicum*. This high-purity compound is a critical intermediate and reference standard in pharmaceutical research and development, valued for its specific biological activity. It is primarily sought by manufacturers and research institutions in the life sciences sector for the development and quality control of therapeutic agents, particularly in the study of anti-inflammatory and anti-gout mechanisms.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the identification, assay, and purity testing of pharmaceutical products and raw materials.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the synthesis and research of advanced pharmaceutical compounds targeting inflammatory conditions.
• Biochemical Research: Employed in in-vitro and in-vivo studies to investigate cellular mechanisms related to microtubule dynamics and mitosis.
• Analytical Chemistry: Utilized as a high-purity calibrant in chromatographic methods (HPLC, LC-MS) for method development and validation.
• Natural Product Isolation & Standardization: Acts as a marker compound for the quality control and standardization of plant extracts containing colchicine-related alkaloids.

Basic Information

Product Name	Colchicoside
CAS No.	477-29-2
Molecular Formula	C27H33NO11
Molecular Weight	547.55 g/mol
Synonyms	Colchicoside; 3-Demethylcolchicine 3-glucoside; Colchicine glucoside; NSC-75744; (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide β-D-glucopyranoside; Colchicosidum
EINECS	207-513-9

Quality Control

Our Colchicoside is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.