Description

Homolycorine CAS NO 477-20-3 is a naturally occurring alkaloid compound derived from plants of the Amaryllidaceae family. This bioactive molecule is of significant interest for its unique structural framework and potential as a lead compound in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector. Its distinct chemical properties make it a valuable intermediate for synthesizing novel therapeutic agents and for advanced biochemical studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and synthesis of new drug candidates, particularly in neuroscience and oncology.
• Biochemical Research: Used as a tool compound to study biological pathways, enzyme interactions, and cellular mechanisms due to its specific alkaloid activity.
• Academic & Contract Research: Employed in university and CRO laboratories for pharmacological screening, structure-activity relationship (SAR) studies, and natural product chemistry.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques.
• Chemical Synthesis: Provides a complex, chiral scaffold for organic chemists to develop novel synthetic methodologies and create derivatives with modified biological profiles.

Basic Information

Product Name	Homolycorine
CAS No.	477-20-3
Molecular Formula	C16H17NO4
Molecular Weight	287.31 g/mol
Synonyms	Homolycorine; 6,7-Didehydro-3,14-dihydroxy-4,5-epoxy-6-methylgalanthan-1-one; Narciclasine-4,5-oxide; Amaryllidaceae Alkaloid; Lycorine Alkaloid Derivative; 1(2H)-Phenanthridinone, 3,4,5,6,6a,7-hexah- ydro-1,2,9,10-tetrahydroxy-6-methyl-, (1α,2β,9α,10β,6aβ)-; Contact for EINECS details.

Quality Control

Our Homolycorine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry standards for research chemicals to support your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.