Description

Boldine CAS NO 476-70-0 is a prominent aporphine alkaloid naturally found in the leaves and bark of the boldo tree (*Peumus boldus*). This compound is valued for its significant biological activity, serving as a key reference standard and active ingredient in research and development. It is primarily sought after by the pharmaceutical, nutraceutical, and academic research sectors for applications in metabolic, hepatic, and antioxidant studies.

Application

• Pharmaceutical Reference Standard: Used as a primary standard in HPLC and LC-MS methods for the quality control of boldo extract and related herbal products.
• Nutraceutical Ingredient: Incorporated into dietary supplements targeting liver health and digestive support, leveraging its choleretic and antioxidant properties.
• Biochemical Research: Employed in *in vitro* and *in vivo* studies to investigate mechanisms related to inflammation, oxidative stress, and metabolic disorders.
• Cosmeceutical Formulations: Utilized in advanced skincare products for its antioxidant potential to protect against environmental stressors.
• Natural Product Isolation & Synthesis: Serves as a benchmark compound in the isolation, purification, and synthetic modification of aporphine alkaloids.

Basic Information

Product Name	Boldine
CAS No.	476-70-0
Molecular Formula	C19H21NO4
Molecular Weight	327.37 g/mol
Synonyms	1,10-Dimethoxy-6aβ-aporphine-2,9-diol; (+)-Boldine; (6aS)-1,10-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol; Boldina; NSC 221164; Boldine Alkaloid
EINECS	207-511-4

Quality Control

Our Boldine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets high-grade standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.