Description

Chelidonine is a benzylisoquinoline alkaloid naturally found in plants of the *Chelidonium majus* (greater celandine) species. This compound serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for research and development in the life sciences. It is primarily utilized by professionals in the pharmaceutical, biotechnology, and academic research sectors for pharmacological studies, analytical method development, and as a building block for novel therapeutics.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of related substances in drug development and quality control laboratories.
• Biochemical Research: Serves as a key reagent in studies investigating its pharmacological properties, including potential effects on cell proliferation and enzyme inhibition.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed as a starting material or intermediate in the synthetic pathways for more complex pharmaceutical compounds.
• Analytical Chemistry: Utilized as a high-purity standard for calibrating instruments and validating analytical methods such as HPLC and LC-MS.
• Natural Product Isolation & Study: Acts as a marker compound in the extraction, characterization, and standardization of plant-derived formulations.

Basic Information

Product Name	Chelidonine
CAS No.	476-32-4
Molecular Formula	C₂₀H₁₉NO₅
Molecular Weight	353.37 g/mol
Synonyms	Chelidonine; (-)-Chelidonine; L-Chelidonine; α-Chelidonine; Dihydrochelerythrine; 5,6,13,13a-Tetrahydro-8,9-dimethoxy-6-methyl-[1,3]benzodioxolo[5,6-c]-2,3,9,10-tetrahydroxyprotoberberine; Stylophorin
EINECS	207-506-8

Quality Control

Our Chelidonine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the exacting standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing specific test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.