Description

Boldine Dimethyl Ether is a chemically modified derivative of the natural alkaloid boldine, characterized by the methylation of its phenolic hydroxyl groups. This modification enhances its lipophilicity and stability, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel compounds and as a reference standard.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents and analogs for pharmacological studies.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related substances.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) of aporphine alkaloids and their biological effects.
• Process Chemistry: Serves as a starting material or intermediate in scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and exploring new organic reactions.

Basic Information

Product Name	Boldine Dimethyl Ether
CAS No.	475-81-0
Molecular Formula	C21H25NO4
Molecular Weight	355.43 g/mol
Synonyms	1,10-Dimethoxy-6aβ-aporphine-2,9-diol; Boldine 2,9-dimethyl ether; 2,9-Dimethoxy-1,10-dihydroxyaporphine; NSC 51046; 6a,7-Didehydro-4,5,6,6a-tetrahydro-1,10-dimethoxy-7H-dibenzo[de,g]quinoline-2,9-diol; 1,2,9,10-Tetrahydroxyaporphine dimethyl ether
EINECS	Contact for details

Quality Control

Our Boldine Dimethyl Ether is produced and tested to meet high-purity standards suitable for research and development. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided to ensure traceability and quality assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.