Description

Isocorydine Hydrochloride is a high-purity alkaloid derivative with significant pharmacological research interest. This compound serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for advanced drug discovery and development programs. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals targeting neurological and oncological applications.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis and study of novel therapeutic agents.
• Neurological Studies: Investigation of its potential effects on central nervous system targets for academic and pre-clinical research.
• Oncology Research: Evaluation of anti-proliferative and apoptotic properties in various cancer cell line studies.
• Analytical Chemistry: Serves as a certified reference material (CRM) for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Biochemical Assays: Used as a precise reagent in enzyme inhibition studies and receptor binding assays.
• Fine Chemical Synthesis: A building block for the preparation of more complex alkaloid derivatives and specialized chemical entities.

Basic Information

Product Name	Isocorydine Hydrochloride
CAS No.	475-67-2
Molecular Formula	C20H23NO4·HCl
Molecular Weight	377.86 g/mol
Synonyms	Isocorydine HCl; (+)-Isocorydine hydrochloride; NSC 176323; 6-Methyl-2,3,9,10-tetramethoxyberbin-7-ol hydrochloride; Corydine isomer hydrochloride; 1,2,9,10-Tetramethoxy-6-methyl-4H-dibenzo[de,g]quinolin-7-ol hydrochloride; (13aS)-2,3,9,10-Tetramethoxy-6-methyl-13aH-berbin-7-ol hydrochloride
EINECS	Contact for details

Quality Control

Our Isocorydine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.