Description

Bufothionine is a specialized organic sulfur compound, identified by CAS NO 475-39-8, belonging to the class of bufadienolides. This compound is valued for its unique structural framework, which serves as a critical intermediate and reference standard in advanced chemical synthesis and pharmacological research. It is primarily sought by professionals in the pharmaceutical development, biotechnology, and fine chemical synthesis sectors for its role in producing novel therapeutic agents and conducting high-purity analytical studies.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control and method validation in drug development and regulatory submissions.
• Biochemical Research: Serves as a key intermediate or substrate in studies investigating enzyme activity, metabolic pathways, and the structure-activity relationships of bioactive molecules.
• Fine Chemical Synthesis: Acts as a crucial building block for the synthesis of complex natural product analogs and novel bufadienolide derivatives with potential biological activity.
• Academic & Discovery Research: Utilized in university and institutional labs for exploratory research in medicinal chemistry, toxicology, and natural product chemistry.

Basic Information

Product Name	Bufothionine
CAS No.	475-39-8
Molecular Formula	C26H34N2O5S
Molecular Weight	486.63 g/mol
Synonyms	14β,15β-Epoxy-3β-(sulfooxy)-14,15-seco-5β-bufa-20,22-dienolide; Bufothionine; 3β-Sulfooxy-14,15-epoxy-14,15-seco-5β-bufa-20,22-dienolide; 3-(Sulfooxy)-14,15-epoxy-14,15-seco-5β-bufa-20,22-dienolide; Bufothionin; Bufothioninum
EINECS	Contact for details

Quality Control

Our Bufothionine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.