Description

(2R,5R)-10-Oxoaspidofractinine-3β-Carboxylic Acid Methyl Ester CAS NO 464-68-6 is a high-purity, chiral alkaloid derivative with a complex pentacyclic structure. This compound serves as a critical advanced pharmaceutical intermediate and a valuable scaffold in organic synthesis for developing novel bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on producing specialized APIs and reference standards.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex natural product analogs and potential therapeutic agents.
• Research Chemical: Used in academic and industrial research for studying structure-activity relationships (SAR) and alkaloid chemistry.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: A versatile precursor for further chemical modifications, enabling the exploration of new chemical space in medicinal chemistry.
• Biochemical Research: Potential tool compound for investigating biological pathways and enzyme interactions related to its core structure.

Basic Information

Item	Details
Product Name	(2R,5R)-10-Oxoaspidofractinine-3β-Carboxylic Acid Methyl Ester
CAS No.	464-68-6
Molecular Formula	C₂₁H₂₄N₂O₃
Molecular Weight	352.43 g/mol
Synonyms	10-Oxoaspidofractinine-3β-carboxylic acid methyl ester; Methyl (2R,5R)-10-oxoaspidofractinine-3β-carboxylate; Aspidofractinine-3β-carboxylic acid, 10-oxo-, methyl ester, (2R,5R)-; Kopsanone methyl ester (stereospecific); 3β-Carbomethoxy-10-oxoaspidofractinine
EINECS	Contact for details

Quality Control

Our (2R,5R)-10-Oxoaspidofractinine-3β-Carboxylic Acid Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.