Description

2-Aminopurine is a purine derivative and a fluorescent nucleobase analog of adenine, widely recognized for its role as a molecular probe in biochemistry and molecular biology. Its unique photophysical properties make it an invaluable tool for studying nucleic acid structure, dynamics, and protein-nucleic acid interactions. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors, where precise molecular tools are required for advanced research and development.

Application

• Fluorescent Probe in Nucleic Acid Research: Used to study DNA and RNA structure, conformation, and dynamics due to its base-pairing properties and sensitivity to local environment.
• Biochemical Assay Development: Serves as a key component in the development of fluorescence-based assays for enzyme activity, such as polymerases and helicases.
• Molecular Beacon and Aptamer Design: Incorporated into oligonucleotides to create sensitive biosensors and diagnostic tools.
• Protein-Nucleic Acid Interaction Studies: Utilized to probe binding events and conformational changes through fluorescence quenching or enhancement.
• Pharmaceutical Intermediate: Acts as a building block in the synthesis of novel nucleoside analogs with potential therapeutic applications.
• Academic and Industrial R&D: A fundamental reagent for basic research in genetics, virology, and drug discovery programs.

Basic Information

Product Name	2-Aminopurine
CAS No.	452-06-2
Molecular Formula	C5H5N5
Molecular Weight	135.13 g/mol
Synonyms	2-AP; 2-Amino-9H-purine; 2-Amino-7H-purine; 2-Aminohypoxanthine; 9H-Purin-2-amine; Isoadenine; Purin-2-ylamine; 2-Amino-1H-purine; 2-Aminopurine, free base
EINECS	207-198-5

Quality Control

Our 2-Aminopurine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality control protocols are designed to meet the stringent requirements of advanced biochemical and pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.