Description

12-Oxo-3,4-Seco-5β-Cholane-3,4,24-Trioic Acid is a high-purity, multi-functional bile acid derivative and a key intermediate in advanced organic synthesis. This compound is valued for its defined steroidal backbone, which makes it a crucial building block for the research and development of novel pharmaceuticals and bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of steroidal drugs, hormone analogs, and other bioactive compounds.
• Biochemical Research: Used as a reference standard or substrate in metabolic pathway studies and enzyme inhibition assays.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for constructing complex molecular architectures in organic chemistry.
• Analytical Standard: Employed in analytical laboratories for method development, calibration, and quality control testing.
• Material Science Research: Investigated for potential use in the development of specialized polymers or surface-active agents.

Basic Information

Product Name	12-Oxo-3,4-Seco-5β-Cholane-3,4,24-Trioic Acid
CAS No.	438-06-2
Molecular Formula	C24H34O7
Molecular Weight	434.52 g/mol
Synonyms	3,4,24-Trihydroxy-12-oxo-5β-cholan-3,4,24-trioic acid; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid 12-oxo derivative; 12-Oxo-3,4-seco-5β-cholane-3,4,24-trioic acid; 12-Ketolithocholic acid derivative; Seco-bile acid triacid; 5β-Cholane-3,4,24-trioic acid, 12-oxo-3,4-seco-; Lithocholic acid 12-oxo seco-triacid
EINECS	Contact for details

Quality Control

Our 12-Oxo-3,4-Seco-5β-Cholane-3,4,24-Trioic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.