Description

(+)-Fangchinoline CAS NO 436-77-1 is a high-purity, naturally occurring bisbenzylisoquinoline alkaloid isolated from the *Stephania* genus of plants. This compound is of significant interest for its role as a key reference standard and active research material in pharmacological and phytochemical studies. It is primarily sought by research institutions, pharmaceutical R&D departments, and manufacturers of analytical standards for applications in neuroscience, cardiovascular research, and traditional medicine validation.

Application

• Pharmacological Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of herbal extracts and traditional medicines.
• Neuroscience Research: Investigated for its potential modulatory effects on neuronal calcium channels and neurotransmitter systems.
• Cardiovascular Studies: Employed in research exploring its vasodilatory and anti-hypertensive properties.
• Anti-inflammatory & Immunomodulatory Research: Serves as a lead compound in studies targeting inflammatory pathways and immune response modulation.
• Phytochemical & Natural Product Analysis: Essential for the identification, purity assessment, and standardization of botanical ingredients in nutraceuticals.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific biological mechanisms and signal transduction pathways.

Basic Information

Product Name	(+)-Fangchinoline
CAS No.	436-77-1
Molecular Formula	C37H40N2O6
Molecular Weight	608.73 g/mol
Synonyms	Fangchinoline; (+)-Fangchinoline; Fangchinolin; NSC 146397; (1S)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman-1-ol; (S)-Fangchinoline; Fangchinoline (S-form); Alkaloid F from *Stephania tetrandra*
EINECS	Contact for details

Quality Control

Our (+)-Fangchinoline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.