Description

Costaclavin CAS NO 436-41-9 is a high-purity ergot alkaloid derivative, a key intermediate in the synthesis of complex pharmaceutical compounds. Its precise chemical structure makes it an essential building block for research and development in advanced therapeutic areas. This product is primarily targeted at the pharmaceutical, biotechnology, and advanced organic synthesis sectors, where consistent quality and reliable supply are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex ergoline-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and starting material in neurological and receptor-binding studies.
• Organic Synthesis: Serves as a versatile chiral building block for constructing complex natural product analogs and novel chemical entities.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized drug candidates.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and pharmacology projects.

Basic Information

Product Name	Costaclavin
CAS No.	436-41-9
Molecular Formula	C16H18N2O2
Molecular Weight	270.33 g/mol
Synonyms	Costaclavine; 9,10-Didehydro-6-methyl-8β-ergoline-8-methanol; 8β-Hydroxymethyl-6-methyl-9,10-didehydroergoline; 8β-(Hydroxymethyl)-6-methylergoline-9-ene; (8β)-9,10-Didehydro-6-methylergoline-8-methanol; Agroclavine-8β-methanol
EINECS	Contact for details

Quality Control

Our Costaclavin is manufactured under strict quality management systems to ensure batch-to-batch consistency and purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent in-house specifications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.