Description

Ac-Glu-Glu-Val-Val-Ala-Cys-Pna is a synthetic peptide substrate designed for biochemical and pharmaceutical research. This compound is critical for studying enzyme kinetics and inhibition, particularly for proteases and other hydrolytic enzymes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers for assay development and high-throughput screening.

Application

• Protease/Enzyme Substrate: Used as a specific chromogenic or fluorogenic substrate for studying the activity, kinetics, and inhibition profiles of target proteases.
• Pharmaceutical Research: Employed in drug discovery programs to screen and characterize potential therapeutic compounds that modulate enzyme activity.
• Diagnostic Development: Serves as a key component in the formulation of in vitro diagnostic assays for detecting specific enzymatic activity related to disease states.
• Biochemical Research: A fundamental tool for investigating protein-protein interactions, signal transduction pathways, and cellular processes involving specific peptide cleavage.
• Quality Control Reagent: Used in the biomanufacturing industry as a reference standard or QC reagent for validating the purity and activity of enzyme-based products.

Basic Information

Item	Detail
Product Name	Ac-Glu-Glu-Val-Val-Ala-Cys-Pna
CAS No.	389868-12-6
Molecular Formula	C34H49N9O12S
Molecular Weight	783.87 g/mol
Synonyms	Ac-EEVVAC-pNA; N-Acetyl-Glu-Glu-Val-Val-Ala-Cys-4-Nitroanilide; Acetyl-Glutamyl-Glutamyl-Valyl-Valyl-Alanyl-Cysteine 4-Nitroanilide; Ac-EEVVAC-pNA Substrate; Protease Substrate 389868-12-6; pNA Peptide Substrate; Chromogenic Peptide Substrate; 4-Nitroanilide Peptide Derivative
EINECS	Contact for details

Quality Control

Our Ac-Glu-Glu-Val-Val-Ala-Cys-Pna is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; Sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.