Description

H-D-Phe-Homopro-Arg-Pna 2 Acetate is a high-purity, synthetic peptide derivative used as a critical biochemical tool and research intermediate. This compound is valued for its specific sequence and functional groups, making it essential for advanced proteomics and enzyme-substrate interaction studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on developing novel therapeutic agents and diagnostic assays.

Application

• Biochemical Research: Serving as a specialized substrate or inhibitor in enzymatic assays to study protease activity and kinetics.
• Pharmaceutical Development: Acting as a key intermediate in the synthesis of more complex peptide-based drug candidates and pharmacologically active compounds.
• Proteomics & Diagnostics: Used in the development of sensitive diagnostic kits and reagents for detecting specific enzyme levels or activity in biological samples.
• Academic Research: A vital tool in university and institutional labs for investigating cell signaling pathways, protein-protein interactions, and peptide metabolism.
• Peptide Library Synthesis: Employed as a building block in the combinatorial synthesis of peptide libraries for high-throughput screening against various biological targets.

Basic Information

Product Name	H-D-Phe-Homopro-Arg-Pna 2 Acetate
CAS No.	386253-60-7
Molecular Formula	C31H44N8O6 • 2(C2H4O2)
Molecular Weight	Contact for details
Synonyms	H-D-Phenylalanyl-homoprolyl-arginyl-p-nitroanilide diacetate; D-Phe-HomoPro-Arg-pNA • 2AcOH; Phe-Hpr-Arg-pNA; Thrombin Substrate II; Chromogenic Substrate for Thrombin; Tos-Gly-Pro-Arg-pNA analog; S-2238 Analog; Benzoyl-Phe-Val-Arg-pNA related compound
EINECS	Contact for details

Quality Control

Every batch of H-D-Phe-Homopro-Arg-Pna 2 Acetate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with rigorous internal specifications suitable for research and development applications. A detailed Certificate of Analysis (COA) documenting purity, identity, and other critical parameters is provided with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	Conforms to theoretical
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.