Description

1,2-Di-o-Tetradecyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is a high-purity synthetic phospholipid, specifically a sodium salt of a phosphatidylglycerol derivative with defined C14 alkyl chains. This compound is critical for creating stable, well-defined lipid structures essential for advanced research and formulation development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing sophisticated drug delivery systems such as liposomes and lipid nanoparticles (LNPs).

Application

• Liposome Formulation: A key structural lipid for constructing stable, uniform liposomal vesicles for drug encapsulation.
• mRNA-LNP Delivery Systems: Used as a helper or structural lipid in the design of lipid nanoparticles (LNPs) for nucleic acid delivery, including mRNA vaccines and therapies.
• Model Membrane Studies: Employed in biophysical research to create synthetic lipid bilayers with specific properties for studying membrane-protein interactions and dynamics.
• Pharmaceutical Excipient: Serves as a functional excipient in advanced parenteral formulations to improve stability and biocompatibility.
• Diagnostic Reagent Development: Used in the formulation of contrast agents or diagnostic probes requiring specific surface charge and stability.
• Biomimetic Coatings: Applied in surface science to create biocompatible, phospholipid-based coatings for medical devices and implants.

Basic Information

Product Name	1,2-Di-o-Tetradecyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt)
CAS No.	384835-62-5
Molecular Formula	C₃₄H₆₈NaO₁₀P
Molecular Weight	690.86 g/mol
Synonyms	1,2-Ditetradecyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; 1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt); DMPG-Na; 1,2-Di-O-tetradecyl-rac-glycero-3-phosphoryl-1'-rac-glycerol sodium salt; PG(14:0/14:0) sodium salt; Phosphatidylglycerol (14:0/14:0) sodium salt; Sodium 1,2-ditetradecyl-sn-glycero-3-phospho-(1'-rac-glycerol); Synthetic PG lipid sodium salt
EINECS	Contact for details

Quality Control

Our 1,2-Di-o-Tetradecyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, NMR for structural verification, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports critical applications in pharmaceutical R&D and GLP/GMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.