Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Cap Biotinyl) (Sodium Salt) is a high-purity, synthetic phospholipid derivative functionalized with a biotin cap, designed for advanced bioconjugation and surface immobilization. This compound is critical for creating stable, high-affinity linkages in biomolecular research and diagnostic applications, offering superior specificity and low non-specific binding. It is primarily utilized by researchers and manufacturers in the life sciences sector, particularly for developing liposomal drug delivery systems, biosensors, and affinity chromatography matrices.

Application

• Liposome and Nanoparticle Functionalization: For the targeted delivery of therapeutics, where biotin-streptavidin binding enables precise surface modification and ligand attachment.
• Biosensor and Diagnostic Assay Development: As a key component for immobilizing capture molecules (e.g., antibodies, receptors) onto sensor surfaces or microplate wells.
• Affinity Chromatography and Purification: Used to create stationary phases for the isolation and purification of streptavidin/avidin-tagged proteins or other biomolecules.
• Cell Membrane Research and Labeling: Incorporation into lipid bilayers to study membrane dynamics or for fluorescent labeling via biotin-binding probes.
• Drug Discovery and High-Throughput Screening (HTS): As a tool compound for developing assays that rely on specific lipid-protein interactions.
• Biomaterial and Surface Engineering: Coating materials to create biofunctional surfaces that promote specific cellular interactions or reduce fouling.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Cap Biotinyl) (Sodium Salt)
CAS No.	384835-52-3
Molecular Formula	C59H108N3NaO11P
Molecular Weight	1101.5 g/mol
Synonyms	Biotin Cap PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cap biotinyl); Biotinyl Cap Phosphatidylethanolamine; Biotin-DPPE; DPPE-Biotin; Biotinylated DPPE; N-((6-(Biotinoyl)amino)hexanoyl)-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine, Sodium Salt; 16:0 Biotinyl Cap PE
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Cap Biotinyl) (Sodium Salt) is manufactured under strict quality systems to ensure batch-to-batch consistency for research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, DMSO; forms micelles in water
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.