Description

1-Myristoyl-2-[12-[(7-Nitro-2-,1,3-Benzoxadiazol-4-Yl)Amino]Dodecanoyl]-Sn-Glycerol-3-Phospho-Rac-(1-Glycerol) Sodium Salt is a high-purity, fluorescently labeled phospholipid derivative, specifically designed for advanced research and diagnostic applications. This compound serves as a critical tool for probing membrane dynamics, lipid trafficking, and cellular signaling pathways due to its NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) fluorophore. It is essential for researchers and developers in pharmaceutical discovery, biophysics, and cell biology who require reliable, well-characterized fluorescent probes for sensitive assays.

Application

• Fluorescent Biomembrane Probes: Used to label and visualize artificial lipid bilayers (liposomes) and cellular membranes in real-time studies.
• Lipid Trafficking & Metabolism Research: Tracks the movement, localization, and enzymatic processing of phospholipids within live cells.
• Lipoprotein & Vesicle Studies: Incorporated into HDL, LDL, or exosomes to study their formation, stability, and cellular uptake mechanisms.
• Enzyme Activity Assays: Serves as a substrate for phospholipases (e.g., PLA1, PLA2) and other lipid-modifying enzymes in high-throughput screening.
• Drug Delivery System Development: Acts as a traceable component in the formulation and quality control of liposomal drug carriers.
• Model Membrane Systems: A key component in constructing giant unilamellar vesicles (GUVs) or supported lipid bilayers (SLBs) for biophysical research.
• Apoptosis & Cell Signaling Studies: Utilized to investigate the role of phosphatidylglycerol derivatives and their analogs in cellular processes.

Basic Information

Product Name	1-Myristoyl-2-[12-[(7-Nitro-2-,1,3-Benzoxadiazol-4-Yl)Amino]Dodecanoyl]-Sn-Glycerol-3-Phospho-Rac-(1-Glycerol) Sodium Salt
CAS No.	384833-03-8
Molecular Formula	C₄₃H₇₁N₄O₁₄P • Na
Molecular Weight	889.01 g/mol (for free acid, sodium salt MW to be confirmed)
Synonyms	NBD-PG; 1-Myristoyl-2-{12-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phospho-(1'-rac-glycerol) Sodium Salt; NBD Phosphatidylglycerol; Fluorescent PG; 1-Myristoyl-2-(NBD-dodecanoyl)-sn-glycero-3-phosphoglycerol Sodium Salt; NBD C12-HPC PG; NBD-labeled PG; PG-NBD
EINECS	Contact for details

Quality Control

Our 1-Myristoyl-2-[12-[(7-Nitro-2-,1,3-Benzoxadiazol-4-Yl)Amino]Dodecanoyl]-Sn-Glycerol-3-Phospho-Rac-(1-Glycerol) Sodium Salt is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, mass spectrometry for identity confirmation, and fluorescence spectroscopy for performance validation. Certificates of Analysis (COA) detailing lot-specific results are provided to ensure traceability and support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (MS)	Complies (M+Na)+
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Area % at 254 nm or fluorescence detection)
Solubility	Soluble in chloroform, methanol, DMSO
Fluorescence Properties	λex ~465 nm, λem ~535 nm (in methanol)
Water Content (KF)	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.