Description

1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine, Pyrene-Labeled is a high-purity, fluorescently tagged phospholipid essential for advanced membrane biophysics and cell biology research. This compound serves as a critical tool for studying lipid dynamics, membrane fusion, and cellular trafficking due to the pyrene fluorophore's unique excimer formation properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors for developing lipid-based delivery systems and sophisticated analytical assays.

Application

• Membrane Biophysics Research: As a fluorescent probe for investigating lipid bilayer properties, phase transitions, and lateral diffusion.
• Liposome & Nanoparticle Development: For tracking the stability, cellular uptake, and intracellular fate of lipid-based drug delivery vehicles.
• Cell Biology Studies: To visualize and quantify membrane fusion events, endocytosis, and intracellular trafficking pathways.
• Diagnostic Assay Development: As a key component in fluorescence-based sensors and kits for detecting enzymatic activity or biomolecular interactions.
• Model Membrane Systems: In the preparation of giant unilamellar vesicles (GUVs) or supported lipid bilayers (SLBs) for controlled experiments.
• Protein-Lipid Interaction Analysis: To study the binding and functional modulation of membrane proteins by specific lipid environments.

Basic Information

Product Name	1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine, Pyrene-Labeled
CAS No.	384832-93-3
Molecular Formula	C81H134NO8P
Molecular Weight	1248.91 g/mol
Synonyms	Pyrene-DOPE; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(1-pyrenesulfonyl); N-(1-Pyrenesulfonyl)-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; DOPE-Pyrene; Fluorescent DOPE; Pyrene-labeled PE; Pyrene-PE; N-(1-Pyrenesulfonyl)-DOPE
EINECS	Contact for details

Quality Control

Every batch of our Pyrene-Labeled DOPE is produced and analyzed under strict quality protocols to ensure exceptional purity and performance consistency for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, fluorescence properties, and critical impurity profiles. Our quality systems support compliance with relevant standards for research-grade biochemicals, ensuring reliable and reproducible results for your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is both light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange waxy solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Pyrene Labeling Efficiency	≥ 98%
Solubility	Soluble in chloroform, ethanol, DMSO
Fluorescence Properties	Excitation ~345 nm, Emission ~375 nm (monomer), ~470 nm (excimer)
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.