Description

Sphingomyelin (Brain, Porcine) is a complex phospholipid and a major component of cell membranes, particularly in neural tissue. This high-purity, natural-sourced lipid is critical for research and development in life sciences, serving as a key building block for membrane models and lipid nanoparticle formulations. It is essential for pharmaceutical researchers, formulation scientists, and diagnostic developers working on neurological studies, drug delivery systems, and advanced biomaterials.

Application

• Lipid Nanoparticle (LNP) Formulation: A crucial structural and functional component in the development of mRNA and other nucleic acid delivery systems.
• Biomembrane & Liposome Research: Used to create artificial membranes and liposomes that accurately mimic the composition and behavior of neural cell membranes for biophysical studies.
• Cell Culture & Neuroscience: Employed as a supplement in specialized cell culture media to study cell signaling, apoptosis, and neuronal function.
• Pharmaceutical Excipient: Investigated for its potential as a stabilizing agent and functional excipient in advanced parenteral formulations.
• Diagnostic Reagent Manufacturing: Serves as a raw material in the production of reagents and kits for clinical diagnostics and biochemical assays.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for lipid analysis via HPLC, MS, or NMR.

Basic Information

Product Name	Sphingomyelin (Brain, Porcine)
CAS No.	383907-91-3
Molecular Formula	Typically C41H83N2O6P (for a common species; mixture)
Molecular Weight	~731.1 g/mol (for C41 species)
Synonyms	Porcine Brain Sphingomyelin; Sphingomyelin from Porcine Brain; N-Acylsphingosine-1-phosphocholine; (2S,3R,4E)-2-Acylamino-4-octadecene-1,3-diol 1-Phosphocholine; SM; Brain Sphingomyelin; Phosphatidylcholine, sphingo-; LIPOID® SM 80; Avanti Polar Lipid Number 860062
EINECS	Contact for details

Quality Control

Our Sphingomyelin (Brain, Porcine) is manufactured and tested under a strict quality management system. Each batch is analyzed to ensure identity, purity, and consistency, meeting the stringent requirements for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), fatty acid profile, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (Total Sphingomyelin)
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.5 %
Microbial Limits	Meets USP <61> and <62> requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.