Description

4-Methylumbelliferyl2-Acetamido-2-Deoxy-B-D-Galactopyranoside6Sulphatepotassiumsalt is a specialized fluorogenic substrate designed for the sensitive detection and quantification of specific enzymatic activity. This compound matters for its role as a critical reagent in biochemical research and diagnostic assay development, offering high sensitivity and specificity. It is primarily needed by researchers and manufacturers in the life sciences, pharmaceutical, and diagnostic industries for applications in enzymology, high-throughput screening, and biomarker discovery.

Application

• Enzyme Substrate for Sulfatases: Specifically used as a fluorogenic substrate for the detection and kinetic study of N-acetylgalactosamine-6-sulfatase (GALNS) and related sulfatase enzymes.
• Biochemical Research & Assay Development: A key reagent in developing fluorometric assays to study lysosomal storage disorders, such as Morquio A syndrome (Mucopolysaccharidosis IVA).
• Diagnostic Kit Manufacturing: Incorporated into in-vitro diagnostic (IVD) kits for the enzymatic diagnosis of genetic disorders and newborn screening programs.
• High-Throughput Screening (HTS): Utilized in pharmaceutical research for screening compound libraries for potential sulfatase inhibitors or activators in drug discovery campaigns.
• Quality Control in Biologics: Employed in QC laboratories to monitor enzyme activity during the production of recombinant therapeutic enzymes.
• Academic Research: Used in university and institutional labs for fundamental research into glycosaminoglycan (GAG) metabolism and enzyme mechanism studies.

Basic Information

Item	Detail
Product Name	4-Methylumbelliferyl2-Acetamido-2-Deoxy-B-D-Galactopyranoside6Sulphatepotassiumsalt
CAS No.	383160-14-3
Molecular Formula	C18H20KNO13S
Molecular Weight	529.52 g/mol
Synonyms	4-MU-β-D-GalNAc-6S; 4-Methylumbelliferyl N-acetyl-β-D-galactosamine-6-sulfate potassium salt; 4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-galactopyranoside-6-sulfate potassium salt; GALNS Substrate; Fluorogenic GALNS substrate; 6-Sulfated 4-MU-β-D-GalNAc; KMU-β-GalNAc-6S; N-Acetyl-β-D-galactosamine-6-sulfate 4-methylumbelliferyl ester potassium salt
EINECS	Contact for details

Quality Control

Every batch of our 4-Methylumbelliferyl2-Acetamido-2-Deoxy-B-D-Galactopyranoside6Sulphatepotassiumsalt is produced and tested under strict quality management systems. We ensure high purity and consistent performance suitable for critical research and diagnostic applications. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. Certificates of Analysis (COA) with detailed specifications are provided with each shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Optical Rotation	Contact for details
Fluorogenic Activity	Functional in standard GALNS assay
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.