Description

4-Methylumbelliferyl 2-Acetamido-2-Deoxy-4-o-(A-L-Fucopyranosyl)-B-D-Glucopyranoside is a specialized fluorogenic substrate designed for the sensitive detection and quantification of specific glycosidase enzyme activity. This compound is critical for biochemical research and diagnostic applications where precise enzymatic measurement is required. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, enzymology, and diagnostic assay development.

Application

• Enzyme Activity Assays: A fluorogenic substrate for the detection and kinetic study of specific α-L-fucosidase and related glycosidase enzymes.
• Diagnostic Reagent Manufacturing: Used in the formulation of kits for the diagnosis of genetic disorders like fucosidosis and for monitoring enzyme replacement therapies.
• Glycobiology Research: Essential tool for investigating carbohydrate metabolism, lysosomal storage diseases, and the role of specific glycosidases in cellular processes.
• High-Throughput Screening (HTS): Employed in pharmaceutical research to screen for potential inhibitors or activators of target glycosidases.
• Biomarker Detection: Facilitates the development of sensitive assays for enzyme biomarkers in clinical and research samples.
• Quality Control in Bioprocessing: Used to monitor the activity of enzyme preparations used in industrial biocatalysis or therapeutic production.

Basic Information

Product Name	4-Methylumbelliferyl 2-Acetamido-2-Deoxy-4-o-(A-L-Fucopyranosyl)-B-D-Glucopyranoside
CAS No.	383160-13-2
Molecular Formula	C26H33NO14
Molecular Weight	583.54 g/mol
Synonyms	4-MU-Fuc-α(1,4)-GlcNAc; 4-Methylumbelliferyl α-L-Fucopyranosyl-(1→4)-2-acetamido-2-deoxy-β-D-glucopyranoside; 4-MU-α-L-Fuc-(1,4)-β-D-GlcNAc; Fucosidase Substrate; Fluorogenic Fucosidase Substrate; α-L-Fucosidase Substrate 4-MU; 2-Acetamido-2-deoxy-4-O-α-L-fucopyranosyl-β-D-glucopyranoside 4-methylumbelliferyl ester
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl glycoside substrates are produced under stringent conditions to ensure the high purity and batch-to-batch consistency required for sensitive research and diagnostic applications. Each lot undergoes comprehensive analysis including HPLC for purity, spectroscopic identification, and functional activity verification. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Optical Rotation	Contact for details
Functional Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.