Description

[7-(9H-Fluoren-9-Ylmethoxycarbonylamino)-2-Oxo-2H-Chromen-4-Yl]-Aceticacid is a specialized, high-purity chemical building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active compounds. It is primarily utilized by pharmaceutical R&D teams, fine chemical producers, and academic institutions focused on medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis & Modification: Used in Fmoc-based solid-phase peptide synthesis (SPPS) for the controlled introduction of coumarin-based fluorophores or functional groups.
• Fluorescent Probe Development: Acts as a core structure for creating sensitive fluorescent probes and sensors used in biochemical assays and diagnostic research.
• Bioconjugation Chemistry: Enables the labeling and modification of biomolecules (e.g., proteins, antibodies) for imaging and therapeutic applications.
• Material Science Research: Employed in the development of advanced organic materials, including photoresponsive polymers and smart coatings.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting cutting-edge research in organic and bioorganic chemistry.

Basic Information

Item	Details
Product Name	[7-(9H-Fluoren-9-Ylmethoxycarbonylamino)-2-Oxo-2H-Chromen-4-Yl]-Aceticacid
CAS No.	378247-75-7
Molecular Formula	C26H19NO6
Molecular Weight	441.43 g/mol
Synonyms	Fmoc-7-amino-4-carboxymethylcoumarin; 4-Carboxymethyl-7-[(9H-fluoren-9-ylmethoxy)carbonylamino]coumarin; 7-[(Fmoc)amino]-4-(carboxymethyl)coumarin; 7-Fmoc-amino-4-carboxymethylcoumarin; ACMA Fmoc derivative; Coumarin derivative Fmoc-AMC-acetic acid; Fmoc-AMC-CH2COOH; (7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)acetic acid
EINECS	Contact for details

Quality Control

Our production of [7-(9H-Fluoren-9-Ylmethoxycarbonylamino)-2-Oxo-2H-Chromen-4-Yl]-Aceticacid adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.