Description

Epigalanthamine n-Oxide is a high-purity, specialized alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and study of novel acetylcholinesterase inhibitors and other bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on neurological therapeutics and chemical biology. The product is supplied with a commitment to stringent quality control and reliable supply chain integrity for global B2B partners.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel acetylcholinesterase inhibitors and other neuroactive compounds.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control of related APIs.
• Biochemical Research: Employed in enzymatic studies and pharmacological assays to investigate mechanisms of action related to cholinergic systems.
• Academic & Discovery Chemistry: Serves as a starting material or scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Process Development: Used in scaling up and optimizing synthetic routes for the production of galantamine derivatives and analogs.

Basic Information

Product Name	Epigalanthamine n-Oxide
CAS No.	366485-18-9
Molecular Formula	C17H21NO4
Molecular Weight	303.35 g/mol
Synonyms	Epigalanthamine N-Oxide; Galanthamine, N-oxide, (4aS,6R,8aS)-; (4aS,6R,8aS)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol N-oxide; N-Oxide of Epigalanthamine; Lycoramine N-Oxide (related); 366485-18-9
EINECS	Contact for details

Quality Control

Our Epigalanthamine n-Oxide is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Standard quality control includes identity confirmation by spectroscopic methods and purity determination by HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each shipment. We support compliance with relevant guidelines for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.