Description

2,3:4,5-Di-o-Isopropylidene-1-o-Propargyl-β-D-Fructopyranose is a specialized, high-purity carbohydrate derivative featuring a protected fructopyranose core with a reactive propargyl ether group. This compound is a critical advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel active ingredients and chiral synthons.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and metabolic disease research.
• Click Chemistry Substrate: The propargyl group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation, polymer synthesis, and material surface functionalization.
• Glycochemistry Building Block: Used in the preparation of complex carbohydrates, glycoconjugates, and glycomimetics for biological studies and therapeutic development.
• Chiral Auxiliary/Synthon: Exploits the inherent chirality of the fructose backbone for asymmetric synthesis, aiding in the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as an intermediate in developing new, more selective pesticides and herbicides with complex sugar-based structures.
• Material Science: Incorporated into the design of functional polymers, hydrogels, and smart materials with tailored biological or chemical properties.

Basic Information

Product Name	2,3:4,5-Di-o-Isopropylidene-1-o-Propargyl-β-D-Fructopyranose
CAS No.	364733-08-4
Molecular Formula	C15H22O6
Molecular Weight	298.33 g/mol
Synonyms	1-O-Propargyl-2,3:4,5-di-O-isopropylidene-β-D-fructopyranose; 1-Propargyl-2,3:4,5-di-O-isopropylidene-β-D-fructopyranose; Diacetone Fructose Propargyl Ether; DAF-Propargyl; Propargyl Ether of Di-O-isopropylidene-D-fructose; 2,3:4,5-Di-O-isopropylidene-1-O-(2-propynyl)-β-D-fructopyranose; β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-1-O-2-propynyl-
EINECS	Contact for details

Quality Control

Our 2,3:4,5-Di-o-Isopropylidene-1-o-Propargyl-β-D-Fructopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.