Description

Suc-Phe-Arg-4Mβna CAS NO 361544-22-1 is a specialized fluorogenic peptide substrate designed for the sensitive detection and quantification of serine protease activity. This compound is critical for researchers and quality control laboratories requiring precise enzymatic assays. It is primarily utilized in biochemical research, pharmaceutical development, and diagnostic applications where monitoring specific protease functions is essential.

Application

• Biochemical Research: As a selective substrate for studying the kinetics and inhibition of specific serine proteases like thrombin, trypsin, and related enzymes.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) assays to identify and characterize potential protease inhibitor drug candidates.
• Diagnostic Development: Employed in the development of fluorogenic assays for clinical diagnostics to measure protease levels in biological samples.
• Enzyme Characterization: Essential for determining the specific activity, purity, and functionality of protease preparations in biotechnology.
• Quality Control: Used in QC labs for the potency testing of enzyme-based pharmaceuticals and reagents.

Basic Information

Product Name	Suc-Phe-Arg-4Mβna
CAS No.	361544-22-1
Molecular Formula	C30H38N6O7
Molecular Weight	594.66 g/mol
Synonyms	N-Succinyl-Phenylalanyl-Arginine 4-Methoxy-β-Naphthylamide; Suc-F-R-4MβNA; Suc-Phe-Arg-4-Methoxy-β-Naphthylamide; Thrombin Substrate IV; Fluorogenic Thrombin Substrate; Serine Protease Substrate; Benzoyl-Phe-Val-Arg-4-methoxy-2-naphthylamide (common related structure); Boc-Val-Pro-Arg-4MβNA (analog)
EINECS	Contact for details

Quality Control

Our Suc-Phe-Arg-4Mβna is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Conforms to reference in standard assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.