Description

m-Peg3-Aldehyde is a specialized bifunctional polyethylene glycol (PEG) derivative featuring a terminal aldehyde group. This compound is a crucial building block in bioconjugation and pharmaceutical development, enabling the precise attachment of molecules to proteins, peptides, and other biomolecules. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, diagnostics, and advanced material science for creating targeted drug delivery systems, modifying surfaces, and developing novel polymer conjugates.

Application

• Bioconjugation Reagent: Used for site-specific modification of proteins, antibodies, and peptides via reductive amination.
• PEGylation Linker: Serves as a key intermediate in the synthesis of PEGylated therapeutics to enhance solubility, stability, and circulation time.
• Crosslinking Agent: Facilitates the formation of hydrogels and polymer networks for tissue engineering and controlled release applications.
• Surface Functionalization: Modifies nanoparticles, biosensors, and diagnostic assay platforms to introduce aldehyde groups for further coupling.
• Pharmaceutical Intermediate: A critical raw material in the synthesis of antibody-drug conjugates (ADCs) and other complex drug molecules.
• Polymer Chemistry: Acts as a monomer or initiator in the synthesis of functionalized, biocompatible polymers.

Basic Information

Product Name	m-Peg3-Aldehyde
CAS No.	356066-46-1
Molecular Formula	C10H20O5
Molecular Weight	220.26 g/mol
Synonyms	3-[(2,5,8,11-Tetraoxatridecan-13-yl)oxy]propanal; 1,11-Dioxo-3,6,9-trioxa-12-azatetradecane; mPEG3-CHO; Methoxy-PEG3-aldehyde; Aldehyde-PEG3-OMe; 2-[2-(2-Methoxyethoxy)ethoxy]ethoxyacetaldehyde; PEG3 aldehyde methyl ether
EINECS	Contact for details

Quality Control

Our m-Peg3-Aldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines for the production of materials intended for research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.