Description

(R)-(+)-2-Amino-4-Methyl-1,1-Diphenylpentane CAS NO 352535-73-0 is a high-purity chiral amine building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules with specific stereochemistry, enabling the development of novel pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and catalyst development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Agrochemical Research: Serves as a key intermediate in developing novel, stereospecific pesticides and herbicides.
• Catalyst Development: Used in the preparation of chiral catalysts for hydrogenation and other transition metal-catalyzed processes.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & R&D: A valuable reagent for methodological research in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-(+)-2-Amino-4-Methyl-1,1-Diphenylpentane
CAS No.	352535-73-0
Molecular Formula	C18H23N
Molecular Weight	253.38 g/mol
Synonyms	(R)-2-Amino-4-methyl-1,1-diphenylpentane; (R)-(+)-2-Amino-4-methyl-1,1-diphenylpentane; (R)-1,1-Diphenyl-2-amino-4-methylpentane; (R)-α-Methyl-1,1-diphenylpentylamine; (R)-Methadone Intermediate; (R)-Methadone amine; (R)-Methadone precursor; (R)-2-Amino-4-methyl-1,1-diphenylpentane hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our (R)-(+)-2-Amino-4-Methyl-1,1-Diphenylpentane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.