Description

Staphopain B CAS NO 347841-89-8 is a highly specific cysteine protease enzyme produced by *Staphylococcus aureus*, playing a crucial role in bacterial virulence and host-pathogen interactions. This enzyme is of significant value for research into staphylococcal pathogenesis, immune evasion strategies, and the development of novel anti-infective agents. It is primarily needed by biotechnology and pharmaceutical research laboratories, as well as academic institutions focused on microbiology, enzymology, and infectious disease studies.

Application

• Biomedical Research: Investigation of *S. aureus* virulence mechanisms and host protein degradation.
• Drug Discovery: Target validation and screening for novel protease inhibitors as potential antibacterial agents.
• Enzymology Studies: Substrate specificity profiling and kinetic analysis of cysteine proteases.
• Immunology Research: Studying bacterial immune evasion through cleavage of host defense molecules.
• Diagnostic Development: Potential use in assay development for detecting specific protease activity.
• Protein Biochemistry: Tool for controlled proteolysis in complex protein mixture analysis.

Basic Information

Product Name	Staphopain B
CAS No.	347841-89-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Staphopain B; SspB; Staphopain B cysteine protease; *Staphylococcus aureus* cysteine protease B; EC 3.4.22.-; Aureolysin (Note: Aureolysin is a metalloprotease, often researched alongside Staphopain B); Cysteine proteinase B (Staphylococcus).
EINECS	Contact for details

Quality Control

Our Staphopain B is produced and handled under stringent quality protocols to ensure high purity, activity, and batch-to-batch consistency suitable for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, specific activity, and absence of contaminating proteases. We adhere to rigorous in-house specifications designed for the research and biotechnology sectors.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot into single-use quantities upon receipt to maintain optimal activity.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (Activity)	Conforms
Purity (SDS-PAGE)	> 90%
Specific Activity	> XX U/mg (Contact for details)
Protein Content (Bradford)	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.