Description

2-[[(2,6-Di(Methyl-D3)Phenyl)Amino]Carbonyl]-1,1-Dimethyl-Piperidinium Iodide is a deuterated quaternary ammonium salt of significant value in advanced research and development. This compound serves as a critical building block and internal standard in analytical chemistry, particularly for mass spectrometry and nuclear magnetic resonance (NMR) studies. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions engaged in sophisticated chemical synthesis and metabolic pathway analysis.

Application

• Pharmaceutical Research & Development: Acts as a deuterium-labeled internal standard for the precise quantification of active pharmaceutical ingredients (APIs) and their metabolites using LC-MS/MS and GC-MS techniques.
• Metabolomics and Biomarker Discovery: Enables accurate tracking and identification of biochemical pathways in complex biological samples, enhancing data reliability in clinical research.
• Chemical Synthesis Intermediate: Serves as a specialized precursor for synthesizing novel deuterated compounds, where isotopic labeling is required for mechanistic studies or to alter pharmacokinetic properties.
• NMR Spectroscopy: Used as a probe or reference compound in deuterium NMR studies to investigate molecular structure, dynamics, and reaction mechanisms without signal interference from protons.
• Quality Control & Method Development: Employed in analytical laboratories to develop and validate highly specific and sensitive assay methods, ensuring regulatory compliance for new drug applications.

Basic Information

Item	Details
Product Name	2-[[(2,6-Di(Methyl-D3)Phenyl)Amino]Carbonyl]-1,1-Dimethyl-Piperidinium Iodide
CAS No.	345261-08-7
Molecular Formula	C17H21D6IN2O
Molecular Weight	426.36 g/mol
Synonyms	1,1-Dimethyl-2-[[(2,6-bis(trideuteriomethyl)phenyl)amino]carbonyl]piperidinium Iodide; 2-[(2,6-Bis(trideuteriomethyl)phenyl)carbamoyl]-1,1-dimethylpiperidinium Iodide; Deuterated Lidocaine N-Ethyl Quaternary Salt; d6-Lidocaine Quaternary Ammonium Salt; N-(2,6-Dimethyl-d6-phenyl)-1-methyl-2-piperidinecarboxamide Ethiodide; Lignocaine-d6 Quaternary Derivative; Piperidinium, 2-[[(2,6-bis(methyl-d3)phenyl)amino]carbonyl]-1,1-dimethyl-, iodide (1:1)
EINECS	Contact for details

Quality Control

Our 2-[[(2,6-Di(Methyl-D3)Phenyl)Amino]Carbonyl]-1,1-Dimethyl-Piperidinium Iodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chemical and isotopic purity, NMR for structural confirmation, and mass spectrometry for identity verification. We provide comprehensive Certificates of Analysis (COA) detailing all specifications to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.